From biomedcentral.com
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Alt-Drama
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Background:
Overexpression of Aurora-A and mutant Ras (RasV12) together has been detected in human bladder cancer tissue. However, it is not clear whether this phenomenon is a general event or not. Although crosstalk between Aurora-A and Ras signaling pathways has been reported, the role of these two genes acting together in tumorigenesis remains unclear.
Methods:
Real-time PCR and sequence analysis were utilized to identify Ha- and Ki-ras...
More perspectives...
