Apoptosis

New hope for lymphoma sufferers [NBC nine-thirteen-2011] Check out: MeTee.com Help thisYoutube channel and Generate and Publish a t-shirt employing the hyperlink above. This channel is brought to you by MeTee T-Shirts: The location for On-Demand t-shirts. – Signup for the Every day News E mail Subscription: tinyurl.com – Like/Dislike, Comment, Favorite and share on Twitter, Facebook, Google+ to get the word out on this video clip. Sunday September twenty five 2011 9:21 pm If you are...Read Full Story

DAPK2 AntibodyCatalog# : 2323Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFNg induced apoptosis. A novel DAP kinase-related protein was...Read Full Story

ZIPK AntibodyCatalog# : 2067Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high...Read Full Story

RIP3 AntibodyCatalog# : 2283Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3 (1-3). RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3...Read Full Story

PIKE AntibodyCatalog# : 3321Phosphoinositide 3 kinase enhancer (PIKE) is a recently identified nuclear GTPase that interacts with nuclear phosphoinositide 3-kinase (PI3 kinase) to stimulate its lipid kinase activity (1). PIKE exists in multiple isoforms; a shorter C-terminal isoform (PIKE-A) has also been identified as centaurin gamma 1 (reviewed in 2). The longest isoform (PIKE-L) has been shown to bind to the adaptor protein Homer and thereby link to metabotropic glutamate receptors...Read Full Story