Biophysics

Evidence for symmetry in the elementary process of bidirectional torque generation by the bacterial flagellar motor [Biophysics_And_Computational_Biology]

The bacterial flagellar motor can rotate in both counterclockwise (CCW) and clockwise (CW) directions. It has been shown that the sodium ion-driven chimeric flagellar motor rotates with 26 steps per revolution, which corresponds to the number of FliG subunits that form part of the rotor ring, but the size of the backward step is smaller than the forward one. read moreRead Full Story

Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation [Biophysics and Computational Biology]

By strrrrr on | From sciencestage.com

The structural and functional conversion of the nonselective NaK channel to a K+ selective channel (NaK2K) allows us to identify two key residues, Tyr and Asp in the filter sequence of TVGYGD, that participate in interactions central to stabilizing the K+ channel selectivity filter. read moreRead Full Story

Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins [Biophysics and Computational Biology]

By strrrrr on | From sciencestage.com

Many voltage-gated ion channel (VGIC) superfamily members contain six-transmembrane segments in which the first four form a voltage-sensing domain (VSD) and the last two form the pore domain (PD). Studies of potassium channels from the VGIC superfamily together with identification of voltage-sensor only proteins have suggested that the VSD and the PD can fold independently. read moreRead Full Story

Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling [Biophysics and Computational Biology]

By strrrrr on | From sciencestage.com

Linear rate-equilibrium (RE) relations, also known as linear free energy relations, are widely observed in chemical reactions, including protein folding, enzymatic catalysis, and channel gating. Despite the widespread occurrence of linear RE relations, the principles underlying the linear relation between changes in activation and equilibrium energy in macromolecular reactions remain enigmatic. read moreRead Full Story

Deciphering the Kinetic Binding Mechanism of Dimeric Ligands [Molecular Biophysics]

By strrrrr on | From sciencestage.com

Dimeric ligands can be potent inhibitors of protein-protein or enzyme-substrate interactions. They have increased affinity and specificity toward their targets due to their ability to bind two binding sites simultaneously and are therefore attractive in drug design. However, few studies have addressed the kinetic mechanism of interaction of such bivalent ligands. read moreRead Full Story

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Biophysics: High-throughput cell stretcher

A chip on which cells flow through tiny channels can be used to measure the size and deformability of individual cells at a rate of 2,000 per second — several orders of magnitude faster than existing methods. The chip could be used to detect cancer

From nature.com ()

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Biophysics: The price of accuracy

Biological systems can adapt to changes in their environment over a wide range of conditions, but responding quickly and accurately is energetically costly. A study pins down the relationship between energy, speed and accuracy.

From nature.com ()

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MyChiroPractice Announces Strategic Partnership with Chiropractic BioPhysics...

MyChiroPractice, the only research-based chiropractic brand management company in the world, proudly announces its strategic partnership with Chiropractic BioPhysics® - the most scientific, comprehensive, and systematic technique in chiropractic.

From api.bing.com ()

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Caution: Wearing These Can Sabotage Your Health

By Dr. Mercola Dr. James Oschman is an expert in the field of energy medicine, with a Bachelor's Degree in Biophysics and a PhD in Biology from the University of Pittsburgh. As an author of a number of books, he is widely recognized as an authority in the biophysics of energy medicine. In this interview he discusses the practice of "earthing," or grounding. Every modern school of alternative medicine talks about "energy," although they may...

From articles.mercola.com ()

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First Pakistan International Biophysics Symposium

Conference: 1 Jun 2012 - 2 Jun 2012, Pakistan. Organized by Dr. M. H. S. Bukhari.

From feedburner.com ()

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