T-Cell Leukemia
T-Cell Leukemia
T-cell leukemia is a disease in which certain cells of the lymphoid system called T lymphocytes or T cells are malignant. T cells are white blood cells that normally can attack virus-infected cells, foreign cells, and cancer cells and produce substances that regulate the immune response.
This section focuses on different types of chronic T-cell lymphocytic leukemia, a subtype of chronic lymphocytic leukemia (CLL). A T cell is a type of white blood cell that directly helps body’s immune system fight infection.
The subtypes of T-cell leukemia include:
Large granular lymphocytic leukemia (LGLL). LGLL is a slow-growing T-cell leukemia and is more common in women than in men. The cause of LGLL is unknown, although about 30% of people with LGLL also have rheumatoid arthritis (a chronic disease causing swelling in the joints of the hands, feet, wrists, knees, hips, or shoulders).
T-cell prolymphocytic leukemia (T-PLL). T-PLL is an aggressive subtype of CLL. T-PLL is a rare post-thymic T-cell malignancy characterized by splenomegaly, lymphadenopathy, hepatomegaly, and a poor prognosis. Further clinical investigation is needed to establish a more effective treatment approach for this rare disorder.
Adult T-cell leukemia/lymphoma (ATLL). Depending on the different features, it is subclassified as smoldering, chronic, acute, or adult T-cell lymphoma (cancer of the lymph system). The acute and the adult T-cell lymphoma subtypes grow quickly. ATLL is caused by a retrovirus called the human T-cell leukemia virus (HTLV1).
Please read more on Lymphoblastic Leukemia
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