From biomedcentral.com
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Bone marrow transplants
The infusion of bone marrow into a patient who has been treated with high dose chemotherapy or radiation therapy. Patients may use their own marrow, which in some cases has been frozen.
Background:
The regulation of growth and apoptosis in K562 cells by human bone marrow mesenchymal stem cells (MSCs) from leukemia patients was investigated. Methods: K562 cells were cocultured with leukemic MSCs under serum deprivation. Cell Counting Kit-8 (CCK-8), PI staining, Annexin V/PI binding and FACS assays were used to investigate cell proliferation, cell cycle status, and apoptosis of K562 cells cultures in the presence or absence of...
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