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Celebrity BFFs

See which Hollywood duos have built lasting friendships over the years.

19 of 25

***EMBARGOED FROM ONLINE USAGE OR PUBLICATION UNTIL END OF LIVE TELECAST*** Penelope Cruz (L) and Salma Hayek present on stage during the 77th Annual Academy Awards on February 27, 2005 at the Kodak Theater in Hollywood, California.
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19. Penelope Cruz & Salma Hayek

Penelope Cruz and Salma Hayek were almost in a plane crash while filming Bandidas, and Cruz revealed, "A thought came across my mind that if I were to die at that moment at least I’d die with my best friend." The two are so close that they were once rumored to be more than just friends, but they laughed off those rumors: Cruz said, "We are like sisters."

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