Cholesterol

SCOTTSDALE, Ariz., May 31, 2012 /PRNewswire/ -- Kowa Pharmaceuticals America, Inc. and Eli Lilly and Company (NYSE:LLY) today announced results of the PREVAIL U.S. study (Pitavastatin compaREd with praVAstatin In Lowering LDL-C in the U.S.) which evaluated the efficacy of LIVALO (pitavastatin) 4 mg compared with pravastatin 40 mg in reducing low-density lipoprotein...  

and have a particularly severe form of the disease (Severe HeFH) defined as those people who are maximally treated and still have LDL-C greater than 200 mg/dL (5.1 mmol) with coronary heart disease or greater than 300 mg/dL (7.1 mmol ...  

SCOTTSDALE, Ariz., May 31, 2012 /PRNewswire/ -- Kowa Pharmaceuticals America, Inc. and Eli Lilly and Company (NYSE:LLY) today announced results of the PREVAIL U.S. study (Pitavastatin compaREd with praVAstatin In Lowering LDL-C in the U.S.) which evaluated the efficacy of...  

To assess the relationship between serial serum leptin levels in patients with acute myocardial infarction (AMI) who received thrombolysis and the degree of coronary atherosclerosis, coronary reperfusion, echocardiographic findings, and clinical outcome.  

Today I want to talk to you about safe blood cholesterol levels. What is a safe range for blood cholesterol levels? What is an ideal level of blood cholesterol? The medically acceptable range is a blood cholesterol below 200 mg. per deciliter (dL).  

DUBLIN--(BUSINESS WIRE)--Dublin - Research and Markets (http://www.researchandmarkets.com/research/mzgz2z/generics_in_cardio) has announced the addition of the "Generics in Cardiovascular Diseases Market to 2018 - Loss of Lipitor Market Exclusivities and Impending Patent Expirations of Plavix to Drive Generic Substitution" report to their offering. GBI Research, the leading business intelligence provider, has released its latest research...  

Cholesterol in the body is carried around the bloodstream in the form of what are called 'lipoproteins'. The two main lipoproteins are so-called low-density lipoprotein cholesterol (LDL-cholesterol) and high-density lipoprotein cholesterol (HDL-cholesterol). Conventional wisdom tells us that HDL-C is a marker for cholesterol being cleared from the inside of the arteries, while LDL-C has the capacity to deposit itself in the artery wall...  

A recent study published in The Lancet online last week shows that even the people that are not at high risk of suffering a heart attack or stroke, can benefit from using Statins. A recent study published in The Lancet online last week shows that even the ...  

Background— Whether mitral valve repair during coronary artery bypass grafting (CABG) improves survival in patients with ischemic mitral regurgitation (MR) remains unknown. Methods and Results— Patients with ejection fraction ≤35% and coronary artery disease amenable to CABG were randomized at 99 sites worldwide to medical therapy with or without CABG. The decision to treat the mitral valve during CABG was left to the surgeon. The primary end...  

PITTSBURGH - Mylan Inc. said Tuesday it is now selling a generic version of Pfizer's cholesterol drug Lipitor. Mylan said the Food and Drug Administration approved its version of the drug, which is also known as atorvastatin. Lipitor was the biggest ...  

Teva Pharmaceutical Industries has decided not to launch atorvastatin, a generic version of Pfizer's Lipitor. The decision will help Ranbaxy Laboratories and Dr Reddy's Laboratories gain larger sales of the medicine in the US, the Economic Times of India reported. Teva Americas president and CEO William Marth was quoted by the news agency as saying that the reason for the company to take the decision...  

Background— Low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol are established risk factors for vascular disease, but lipoprotein particle concentrations may be stronger determinants of risk. Methods and Results— Associations between vascular events and baseline concentrations of cholesterol fractions, apolipoproteins B and A1, and lipoprotein particles assessed by nuclear magnetic resonance were...  

Data Presented at the European Atherosclerosis Society Congress Reinforces the ...MarketWatch (press release)Data presented today from the VOYAGER study demonstrate the benefits of aggressive statin therapy with CRESTOR™ (rosuvastatin) in comparison to atorvastatin and simvastatin in high risk patients. VOYAGER is an individual patient data meta-analysis of ...and more »  

The authors pointed out that their previous analysis of studies suggested that statin therapy to reduce LDL cholesterol in people without a history of vascular disease ultimately reduced their risk of heart attacks and strokes by about a fifth. However ...  

Over the long Memorial Day weekend Regeneron and Sanofi added to their stockpile of promising mid-stage data for their PCSK9 drug, which is designed to slash levels of "bad" LDL-cholesterol. Tapped as one of the most promising potential ...  

Background: Niemann-pick C1-like 1 (NPC1L1) is a key protein for intestinal cholesterol transportation. Common single nucleotide polymorphisms (SNPs) in the NPC1L1 gene have been associated with cholesterol absorption and serum lipid levels. The present study was undertaken to explore the possible association of NPC1L1 rs2072183 1735 C > G SNP and several environmental factors with serum lipid levels in the Mulao and Han populations. Methods...  

To track the prevalence of four major CVD risk factors -- high levels of low-density lipoprotein cholesterol (LDL), low levels of high-density lipoprotein (HDL) cholesterol, hypertension, and diabetes -- May and colleagues analyzed NHANES data ...  

Fish is a delicious, healthy alternative to meat if you are craving a little bit of protein, but are also watching your cholesterol levels. Although it is not as commonly consumed as poultry or tofu, there are many ways fish can be incorporated into your meal plans. With a little creativity - and these healthy tips - fish dishes can make a tasty addition to your cholesterol-lowering diet....Read Full Post  

DEAR DR. DONOHUE: I am 43. I am on Lipitor. My father died of a heart attack when he was 52, and his brother, my uncle, died of one at 55. My cholesterol is a bit on the high side. That’s why my doctor put me on Lipitor. I mentioned this ...  

Reuters (and former Newsweek) science reporter Sharon Begley has written a highly readable and informative article in the May/June issue of the Saturday Evening Post on the risk and benefits of statins, the controversial cholesterol-lowering drugs.Currently, as Begley points out, these drugs are being taken by an astounding number of Americans: one-fourth of everybody aged 45 and older.No wonder, as Begley also reports, that U.S. sales of...  

why would your body make something bad for you anyway? LDL stands for low-density lipoprotein, and HDL stands for high-density lipoprotein. LDL is nothing more than a carrier molecule, a pick-up truck that shuttles cholesterol (fat) to the tissues.  

It appears that in some cases, high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol, does not protect against heart disease, and may even be harmful. A new study suggests a subclass of HDL that carries a particular protein is bad for the heart. Previous studies have shown that high levels of HDL cholesterol are strongly linked to low risk of heart disease...  

(NaturalNews) Health-conscious individuals have known the importance of tea consumption for decades, opting for the pleasant tasting beverage over sugary carbonated soft drinks to help prevent metabolic imbalances such as insulin resistance and diabetes.  

why would your body make something bad for you, anyway? LDL stands for low density lipoprotein and HDL stands for high density lipoprotein. LDL is nothing more than a carrier molecule, a pick-up truck that shuttles cholesterol (fat) to the tissues.  

Moderate physical activity does not improve lipoprotein concentrations in obese patients with non-alcoholic fatty liver disease (NAFLD), say researchers. The team found that in these patients, exercise only decreases triglyceride and alanine ...  

NEW DELHI: Israel's Teva Pharmaceuticals will not launch atorvastatin, the generic version of the world's best-selling drug, Lipitor, that will help Indian companies Ranbaxy Laboratories and Dr Reddy's Laboratories garner larger sales of the ...  

The 10th Congress of the ISSFAL (International Society for the Study of Fatty Acids and Lipids) is in full swing in Vancouver, Canada. Experts from the world of omega-3s, fatty acids and lipids are congregating for five days of presentation and discussion of the latest research in this multi-million dollar segment.  

There is no such thing as "good" or "bad" cholesterol. LDL stands for low-density lipoprotein, and HDL stands for high-density lipoprotein. LDL is nothing more than a carrier molecule, that shuttles cholesterol (fat) to the tissues. You don't ...  

A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol, may not protect against coronary heart disease (CHD) and in fact may be harmful. This is the first study to show that a small protein, apolipoprotein C-III (apoC-III), that sometimes resides on the surface of HDL cholesterol may increase the risk of heart disease and that...  

Watching your cholesterol levels doesn't mean that you have to miss out on dessert. Chocolate, fresh fruits, pies -  there is a way that you can try all of these tasty treats without significantly raising your cholesterol levels. Try some of these decadent desserts that will satisfy your taste buds - but not increase your waistline.  

In contrast, HDL cholesterol levels lower than 40 mg/dL may result in a greater risk of heart disease.  In general, low density lipoprotein (LDL) cholesterol is considered high if it is more than 160 mg/dL. On the other hand, the desirable level of LDL ...  

Background: A higher prevalence of coronary heart disease (CHD) in people with diabetes. We investigated the high-density lipoprotein (HDL) subclass profiles and alterations of particle size in CHD patients with diabetes or without diabetes. Methods: Plasma HDL subclasses were quantified in CHD by 1-dimensional gel electrophoresis coupled with immunodetection. Results: Although the particle size of HDL tend to small, the mean levels of low...  

The U.S. Preventive Services Task Force on Tuesday recommended against the use of HRT for the prevention of chronic conditions, such as coronary heart disease, breast cancer and fractures, for postmenopausal women. The panel classified the ...  

Background: The lipid-lowering treatment goal attainment rate is lower for women than for men among Chinese patients, but the reasons for this disparity have not been fully explored yet.ObjectivesTo elucidate the potential factors and the significance of their contributions towards the observed discrepancy in lipid-lowering treatment goal attainment rates between Chinese women and men. Methods: We used data from 1808 patients from 21 tertiary...  

Statin drugs (Lipitor, Mevacor, Zocor, etc.) are used to lower serum cholesterol. They work by going into the liver and blocking key enzymes used in the cholesterol-production process. This is a very effective way to reduce cholesterol ...  

NEW DELHI: Israel's Teva Pharmaceuticals will not launch atorvastatin, the generic version of the world's best-selling drug, Lipitor, that will help Indian companies Ranbaxy Laboratories and Dr Reddy's Laboratories garner larger sales of the ...  

(CBS News) We've heard it all before: There's "good" cholesterol, called high-density lipoprotein (HDL), that provides protective benefits against heart attacks and then there's "bad" LDL cholesterol, which raises risk for heart problems in high levels.  

Exercise stress testing is an important tool in the evaluation of coronary artery disease, but its accuracy varies, and several factors must be considered in its interpretation. International Journal of Clinical Practice  

( Ivanhoe Newswire) -- Statins are a class of drugs that lower the level of cholesterol in the blood by reducing the production of cholesterol by the liver. Now, a new study suggests that using cholesterol-lowering medications known after having a stroke may increase the likelihood of returning home and lessen the chance of dying in the hospital.  

From Yahoo Health. "Researchers on Thursday challenged a tenet of modern medicine that higher levels of "good" cholesterol automatically boost cardiovascular health.In a study published in The Lancet, investigators said they found no evidence to back the belief that higher levels of high-density lipoprotein (HDL) cholesterol routinely reduce the risk of a heart attack.  High concentrations of HDL are one of the big markers for blood tests...  

Shoppers are interested in knowing whether foods with added plant sterols (phytosterols) are healthier because they may help to lower the 'bad' LDL cholesterol. How safe are phytosterols? And how can they benefit your health? The issue is that ...  

Statin drugs, which are commonly used to lower cholesterol levels, may have another significant health benefit. A new study shows statin drugs, like Crestor, Lipitor and Zocor, may also slow the unhealthy growth of the prostate in men with ...  

The commonly consumed type of cholesterol-lowering drug known as statin may aid elderly individuals with high blood pressure prevent getting atrial fibrillation, a heart rhythm abnormality linked with stroke. Many patients opt to buy Zocor for their hypertension which minimizes the occurrence of irregular heartbeat subsequently.  

Statins drugs prescribed to treat high cholesterol may also work to slow prostate growth in men who have elevated PSA levels, according to an analysis led by researchers at Duke University Medical Center. The finding, presented at the annual meeting of the American Urological Association, provides additional insight into the effects of cholesterol-lowing drugs such as statins on the prostate. Previous...  

Online Self-Management Program on Coronary Artery Disease Wins ... for consumer health education was recognized this week with a ClearMark Award from the Center for Plain Language. The Healthwise ® Learn To Earn course on Coronary Artery Disease (CAD ...  

Medtronic has received expanded clearance for a bunch of new indications for its flagship Resolute Integrity drug eluting coronary stent in countries using the CE Mark. It was previously labeled for use in patients with diabetes and multi-vessel disease, but is now also approved for acute coronary syndromes, acute myocardial infarction, unstable angina, bifurcations, in-stent restenosis, total occlusions and chronic total occlusions.Recent...  

Background and Purpose— Studies suggest a protective role for statins after intracerebral hemorrhage, but many failed to assess statin discontinuation, did not include postdischarge outcomes, or did not account for withdrawal of care. We studied the relationship between preintracerebral hemorrhage statin use and in-hospital statin discontinuation on stroke severity and 30-day mortality. Methods— We analyzed data from the Registry of the...  

Researchers at UC have confirmed that fat surrounding the outside of arteries in humans - particularly the left coronary artery - may influence the onset of coronary artery disease, or atherosclerosis, which is the leading cause of death in the U.S. These findings, presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) 2012 Scientific Sessions in Chicago, may help in identifying the molecular...  

In practical terms, stress testing is only useful in those situations where clinicians would feel comfortable not performing coronary angiography in the case of a negative stress test. A recent analysis from a contemporary US population showed that ...  

We performed a meta-analysis of changes in inflammatory biomarkers over the course of exercise interventions in patients with CAD. Methods We searched MEDLINE, Embase, the Cochrane Collaboration, AMED, and CINAHL for studies reporting peripheral ...  

A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called “good” cholesterol, may not protect against coronary heart disease (CHD) and in fact may be harmful.  

Background: Exercise stress testing offers a non-invasive, less expensive way of risk stratification prior to coronary angiography, and a negative stress test may actually avoid angiography. However, previous meta-analyses have not included all ...  

This study was designed to investigate the effect of alpha lipoic acid (ALA) and alpha tocopherol acetate (ATA) on the antioxidant potential, lipid stability and the quality of thebroiler breast meat and meat products. The treatment plan was as (T1 = control feed, T2 = 200 mg ATA + 25 mg ALA/kg feed, T3 = 200 mg ATA + 75 mg ALA/kg feed, T4 = 200 mgATA + 150 mg ALA/kg feed, T5 = Oxidized oil (4%), T6 = 200 mg ATA + 150 mg ALA + Oxidized oil (4...  

Most people, whether healthy or having cardiovascular disease (CVD), would benefit from regular consumption of oily fish, concluded speakers at the EuroPRevent 2012 meeting. While eating whole fish undoubtedly offers the optimum approach for increasing omega-3 intakes in both primary and secondary prevention, delegates heard, supplements have a major role to play in increasing omega-3 intakes for people who do not like fish...  

Over the past three decades, researchers have firmly established that the omega-3 fatty acids in fish oil, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have healthy effects on the heart. Omega-3 fatty acids seem to help both in preventing cardiovascular disease as well as in preventing future heart attacks, strokes, and other adverse events in people who have established cardiovascular disease...  

Background  Data from prospective cohort studies regarding the association between subclinical hyperthyroidism and cardiovascular outcomes are conflicting. We aimed to assess the risks of total and coronary heart disease (CHD) mortality, CHD events, and atrial fibrillation (AF) associated with endogenous subclinical hyperthyroidism among all available large prospective cohorts. Methods  Individual data on 52 674 participants were pooled from...  

A study published in Archives of Internal Medicine reveals that subclinical hyperthyroidism (SCH) may be linked to a greater risk of total mortality, coronary heart disease (CHD) death, as well as incident atrial fibrillation (AF). The findings also indicate that the risk of AF and CHD death is higher when thyrotropin levels are below 0.10 mIU/L. SCH is a relatively common condition defined by low thyrotropin levels with normal concentrations...  

Omega-3 fatty acids may help to reduce the physical harm caused by smoking, according to a new study presented at the World Congress of Cardiology. The study, carried out in Greece, assessed the effect of four-week oral treatment with 2 g/day of omega-3 fatty acids on the arterial wall properties of cigarette smokers. The results showed that short-term treatment with omega-3 fatty acids improves arterial stiffness and moderates the acute...  

Coronary artery disease continues to be a major cause of death in the U.S., killing hundreds of thousands of people per year. However, this disease burden isn't evenly divided between the sexes; significantly more men than women are diagnosed with coronary artery disease each year. The reasons behind this difference aren't well defined. Though some studies have shown that men's hearts become more constricted than women's during exercise...  

High normal blood pressure becomes less of a risk factor for incident cardiovascular disease (CVD) and coronary heart disease (CHD) with age, according to a new study presented today at the World Congress of Cardiology. The study, carried out over 9.3 years, evaluated the risk of different blood pressure categories among 6,273 participants aged 30 years old and above...  

Up until recently it has been long believed that high levels of HDL, high-density lipoprotein, cholesterol would reduce a person’s risk of heart disease. Unfortunately, this topic could be up for debate and more research. A study published ...  

Fats are composed of building blocks called fatty acids ... It also appears to reduce blood levels of the low-density lipoprotein (LDL) ("bad" cholesterol) without affecting the levels of our protective cholesterol, high-density lipoprotein (HDL).  

SANTA BARBARA, Calif., May 28 (UPI) -- Hunter-gatherers who live off the land have lower age-related increases in blood pressure and less risks of atherosclerosis, U.S. researchers say. Study author Michael Gurven, an anthropology professor and ...  

PARIS (dpa-AFX) - Sanofi (SNY) and Regeneron Pharmaceuticals Inc. (REGN) announced additional positive results from a Phase 2 trial of SAR236553/REGN727 (Study 1003, NTC01266876) in pat...  

Background— Up to 25% of patients with untreated Kawasaki disease (KD) and 5% of those treated with intravenous immunoglobulin will develop coronary artery aneurysms. Persistent aneurysms may remain silent until later in life when myocardial ischemia can occur. We sought to determine the prevalence of coronary artery aneurysms suggesting a history of KD among young adults undergoing coronary angiography for evaluation of possible myocardial...  

It was great fun at Mushnik Manor last night for a dinner of poached salmon, sugar snaps, potatoes and pie. Just the ticket for the Plots who are about to fly off to BBQ Land.Speaking of pie and bbq, Plot was reading yesterday about cholesterol. As always there are two schools about your bad cholesterol (LDL) and your good cholesterol (HDL). One school says you must lower LDL dramatically by taking statin drugs, which you must remain on for...  

Background— No simplified bedside risk scores have been created to predict long-term mortality after coronary artery bypass graft surgery. Methods and Results— The New York State Cardiac Surgery Reporting System was used to identify 8597 patients who underwent isolated coronary artery bypass graft surgery in July through December 2000. The National Death Index was used to ascertain patients' vital statuses through December 31, 2007. A Cox...  

Background— Conventional coronary artery bypass grafting performed with the use of cardiopulmonary bypass is a well-validated treatment for patients with ischemic heart disease. Off-pump coronary artery bypass grafting (OPCAB) has been suggested to reduce the number of perioperative complications, especially in elderly patients. Methods and Results— In a multicenter, randomized trial, we assigned 900 patients >70 years of age to conventional...  

I am diagnosed to have coronary artery disease… coronary artery bypass grafting (1995, 2008), diabetes mellitus, anemia, chronic renal disease, and severe obstructive sleep apnea. In spite of the medical advice to remain in the hospital, I am voluntarily ...  

Objective— Low and nontoxic proteasome inhibition has anti-inflammatory, antiproliferative, and antioxidative effects on vascular cells in vitro and in vivo. We hypothesized that low-dose inhibition of the proteasome could provide antiatherogenic protection. The present study investigated the effect of low-dose proteasome inhibition on early lesion formation in low-density lipoprotein receptor–deficient mice fed a Western-type diet. Methods...  

HEART DISEASE BACKGROUND: Heart and blood vessel disease — cardiovascular disease also called heart disease — includes numerous problems, many of which are related to a process called atherosclerosis. Atherosclerosis is a condition that develops when a substance called plaque builds up in the walls of the arteries. This buildup narrows the arteries, making it harder for blood to flow through. If a blood clot forms, it can stop the blood flow...  

Objectives— To determine whether the level of lysophosphatidylcholine (lysoPC) generated by lipoprotein-associated phospholipase A2 (Lp-PLA2) is associated with severity of inflammation in human atherosclerotic plaques. Elevated plasma Lp-PLA2 is associated with increased cardiovascular risk. Lp-PLA2 inhibition reduces atherosclerosis. Lp-PLA2 hydrolyzes low-density lipoprotein–oxidized phospholipids generating lysoPCs. According to in vitro...  

Background: The relationship between TSH and the lipid profile is contradictory because few studies haveexcluded the potential influence of the thyroid hormones (TH). The aim of the present studywas to evaluate the relationship between serum TSH levels and the lipid profile independentof TH. Methods: 1302 CHD patients diagnosed by coronary angiography were retrospectively studied. Theprevalence and distribution of thyroid dysfunction were...  

Last week, Dr. Luke J. Byrnes and the team at Catawba Valley Medical Center’s Heart Catheterization Lab performed the region’s first-ever radial heart catheterization -- a revolutionary diagnostic and treatment technique for coronary artery disease. The method, which goes through the wrist as opposed through the femoral artery in the groin, reduces recovery times, bruising and the risk of severe bleeding. Although the traditional method has...  

Statins (cholesterol lowering drugs) are prescribed to reduce the LDL levels and slightly increase the HDL. “These drugs not only block HMG coenzyme A reductase (the enzyme that prods the liver to make cholesterol) but also blocks Coenzyme Q10 ...  

ScienceDaily (May 21, 2012) — Statins drugs prescribed to treat high cholesterol may also work to slow benign prostate growth in men who have elevated PSA levels, according to an analysis led by researchers at Duke University Medical Center. The finding ...  

A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol, may not protect against coronary heart disease (CHD) and in fact may be ...  

A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called “good” cholesterol, may not protect against coronary heart disease (CHD) and in fact may be harmful.  

The participants' blood pressure, forearm skin blood ... that those who ate dark chocolate had lower levels of blood glucose and "bad" low-density lipoprotein (LDL) cholesterol, and higher levels of "good" high-density lipoprotein (HDL) cholesterol than ...  

WILMINGTON, Del.--(BUSINESS WIRE)--AstraZeneca (NYSE: AZN) today announced results of the LUNAR (Limiting UNdertreatment of Lipids in Acute Coronary Syndrome with Rosuvastatin) study, which showed that CRESTOR 40mg significantly decreased LDL-C or “bad” cholesterol and increased HDL-C or “good” cholesterol compared with atorvastatin 80mg in patients with acute coronary syndrome (ACS). ACS is an umbrella term for conditions that result from...  

Boston, MA – A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called “good” cholesterol, may not protect against coronary heart disease (CHD) and in fact ...  

In this short review, we discuss apolipoprotein B100 and the assembly of very low-density lipoproteins. In particular, we address the nature and importance of co- and posttranslational degradation of apolipoprotein B100 during the assembly process. We also provide a short historical background to the development of the current model for the degradation of apolipoprotein B100.  

A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol, may not protect against coronary heart disease (CHD) and in fact may be ...  

Elevated cholesterol and specifically LDL exists as significant risk factors for heart disease. Food sources of cholesterol lowering substances represent ideal adjuncts to reduce blood levels of cholesterol.Contributor: Dr. Sharon A. TakiguchiPublished: May 21, 2012  

Thousands of heart attacks and strokes could be prevented if the cholesterol-lowering drugs, statins, were more widely prescribed, research suggests. The study of 175,000 patients, in the Lancet, said even very low-risk patients benefited from the medication.  

Rationale: Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the dyslipidemia that leads to cardiovascular morbidity. The central nervous system (CNS), particularly the hypothalamus, regulates hepatic lipid metabolism. Although the underlying neurocircuitry remains elusive, glycine has been documented to enhance CNS N-methyl-d-aspartate (NMDA) receptor-mediated...  

Bern, May 20 (IANS) Statins prevent cancer and reduce death from all causes in heart transplant recipients, independently of cholesterol levels, says a new study. Frank Enseleit, deputy director of heart failure and transplantation at University Hospital ...  

There’s bad news out today for ‘good cholesterol’ drugs. More than five years after New York’s Pfizer made waves for pulling the plug on torcetrapib—a drug designed to elevate blood levels of high-density lipoprotein (HDL), or ‘good’ cholesterol—Roche is now making a similar move. The Swiss pharma giant announced plans to halt development of its own HDL-raising compound, dalcetrapib, after an interim independent review of the company’s pivotal...  

Apontado pelo AMICOR Jorge Ossanai Doubt Cast on the ‘Good’ in ‘Good Cholesterol’By GINA KOLATA Published: May 16, 2012The name alone sounds so encouraging: HDL, the “good cholesterol.” The more of it in your blood, the lower your risk of heart disease. So bringing up HDL levels has got to be good for health. Health Guides: HDL Test |CholesterolOr so the theory went.Now, a new study that makes use of powerful databases of genetic information...  

I just learned that Pfizer has developed an iPhone/iPad app that promotes LIPITOR, the drug company's off-patent lipid-lowering drug. The app is "Recipes 2 Go." It is the first pharmaceutical app that I know of that promotes a prescription drug.Here's what the promo screen on iTunes looks like (click on it for an enlarged view):The description -- shown here in its entirety -- mentions LIPITOR and the FDA-approved indication, which is managing...  

Background: Embolization of atherosclerotic debris from the rupture of a vulnerable atherosclerotic plaque occurs iatrogenically during percutaneous coronary interventions (PCI) and can induce myocardial necrosis. These microembolizations are detected as high intensity transient signals (HITS) using intracoronary Doppler technology. Presentation of the hypothesis In the presented study we will test if abciximab (ReoPro(R)) infusion reduces...  

Background: Paraoxonase-1 (PON1) is an enzyme with numerous functions and receives an increasing interest in clinical and epidemiological studies. Sometimes samples are stored for longer periods at a certain temperature. Therefore the stability of PON1 activity must be checked and retained upon storage for longer periods. Results: In this study the stability of PON1 activity has been tested in human serum samples during storage up to 12 months...  

Background: The vitamin-like omega-3 and omega-6 essential fatty acids are converted in the body to alarge family of hormones which act at selective receptors that occur on nearly every cell andtissue. A relative omega-3 deficit allows overabundant actions of omega-6 hormones todevelop into health disorders. People need simple, explicit information on the balance ofessential fatty acids in their foods to avoid accumulating unintended...  

A new study by Harvard School of Public Health researchers has found that a subclass of high-density lipoprotein cholesterol, the so-called "good" cholesterol, may not protect against coronary heart disease and in fact may be harmful.  

Background— Because of rapid change in lifestyle risk factors, cardiovascular disease has become the leading cause of death in China. We sought to estimate the national levels of serum lipids and lipoproteins among the Chinese adult population. Methods and Results— We conducted a cross-sectional study in a nationally representative sample of 46 239 adults aged ≥20 years. Fasting serum total, high-density lipoprotein, and low-density...  

PARIS, May 17, 2012 /PRNewswire/ -- OrbusNeich today announced that two subgroup analyses from the REMEDEE trial assessing vascular healing of the company's Combo Dual Therapy Stent versus the TAXUS paclitaxel-eluting stent demonstrate an early advantage with the Combo Stent....  

Medications needed to lower your cholesterol can be expensive - and the expense for your medications can multiply if you are taking drugs to treat other chronic health conditions. Sometimes, it might seem like a good idea to cut your cholesterol medications in half to save on your monthly bill to the pharmacy - but can this be done? This article will tell you which pills can be split in half, and which ones you should leave intact....Read...  

Nighttime blood pressure (BP) dipping can be quantified as the ratio of mean nighttime (sleep) BP to mean daytime (awake) BP. People whose dipping ratio is ≥0.90 have been referred to as nondippers, and nondipping is associated with cardiovascular disease events. We examined the relationship between systolic nighttime BP dipping in young adults and the presence of coronary artery calcium (CAC) 10 to 15 years later using data from the...  

Mylan Inc. (Nasdaq:MYL) today announced that it has launched Atorvastatin Calcium Tablets, 10 mg, 20 mg, 40 mg and 80 mg in France, Belgium, the UK, the Netherlands and Ireland. Mylan has received marketing authorization from each country's respective health authority to begin selling its product immediately.  

Remember good cholesterol? You know, HDL cholesterol, the kind that was associated with reduced risk of stroke? Forget it. Now comes a study from researchers at Massachusetts General Hospital and the Broad Institute suggesting that people with genes that boost HDL levels  do not, in fact, have a lower risk of heart attacks. Strange. The Boston Globe reports that the scientists in looked at a gene variation that raises HDL levels, and should...  

Again we get a story about statins and in particular, medicating healthy people. Thousands of heart attacks and strokes could be prevented if the cholesterol-lowering drugs, statins, were more widely prescribed, research suggests. The study of 175,000 patients, in the Lancet, said even very low-risk patients benefited from the medication. The Oxford researchers says the [...]  

THURSDAY, May 17 (HealthDay News) -- Statins -- commonly used cholesterol-lowering drugs -- can significantly lower the risk for heart disease in people with no history of vascular disease, according to a new study. Researchers from the ...  

Last post by: audiosabre (20 May 01:33): Cookbook is sick! It's like the best sounds from the Goldbaby drums rolled into one neat package.Layering is easy with this one. Sits well with the other packs, as usual. No sweat.Superb. I seriously don't know how you're going to raise the bar next time :-o  

Cholesterol-lowering statins, prescribed to some 30 million Americans, have begun to lose a bit of their luster. A set of warnings issued in February by the US Food and Drug Administration require that statin labels include information about the possibility of cognitive side effects such as memory loss and confusion, and an increase in blood sugar levels that could trigger type 2 diabetes. Already on manufacturer websites, the warnings will...  

SAN DIEGO -- Giving statins to cirrhosis patients with heart disease appears to lower the risk ... 95% CI 0.29 to 0.81). Coronary artery disease and non-alcoholic steatohepatitis, on the other hand, were associated with increased mortality ...  

Background— Cardiovascular events occur among statin-treated patients, albeit at lower rates. Risk factors for this "residual risk" have not been studied comprehensively. We aimed to identify determinants of this risk above and beyond lipid-related risk factors. Methods and Results— A total of 9251 coronary patients with low-density lipoprotein cholesterol <130 mg/dL randomized to double-blind atorvastatin 10 or 80 mg/d in the Treating to New...  

Statins -- commonly used cholesterol-lowering drugs -- can significantly lower the risk for heart disease in people with no history of vascular disease, according to a new study.  

by Gwen Dewar, Ph.D. posted in Mom Stories "Eating a high-fructose diet over the long term alters your brain's ability to learn and remember information. But adding omega-3 fatty acids to your meals can help minimize the damage." That’s what UCLA professor Fernando Gomez-Pinilla says. His case? He and Rahul Agrawal taught rats to find... Read... Want to get the full story? Click on the headline above. And thanks for reading the BabyCenter...  

Regina, Saskatchewan (PRWEB) May 28, 2012 The Statin Drugs industry is huge. Evans Consulting Services (Saskatchewan) announced today that it has entered into an agreement with James B. Yoseph and Hannah Yoseph, M.D., (Florida), to market their new book ...  

Pfizer will no longer aggressively market Lipitor (atorvastatin), its former crown jewel and the most lucrative pharmaceutical product ever. At the same time, generic drug manufacturer Ranbaxy posted record revenue for the last business quarter, growth fueled largely by sales of generic atorvastatin in the United States.  

PITTSBURGH and LYON, France, May 11, 2012 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today announced that it has launched Atorvastatin Calcium Tablets, 10 mg, 20 mg, 40 mg and 80 mg in France, Belgium, the UK, the Netherlands and Ireland. Mylan has received marketing authorization from each...  

By ValueMax:Lipitor (atorvastatin), marketed by Pfizer (PFE) to reduce blood cholesterol levels, has been the best-selling pharmaceutical of all time, with aggregate sales of over $125 billion and still going. But the patent has expired, and since November 30, 2011 there have been generics available from Watson Pharmaceuticals (WPI) and Ranbaxy Laboratories, with more certainly to come. Sales of Lipitor peaked at 12.8 billion in 2008. Sales...  

Medical journal says cholesterol-lowering pills can reduce the risk of heart problems, especially in the over-50sMillions of over-50s could safeguard their health by taking statins, according to a study that found the drugs benefit healthy people with no heart problems.The findings could lead to a change in policy by the NHS, which currently restricts cholesterol-lowering statins to those who either have heart disease or have at least a 20...  

Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors regulating lipid ...  

BURLINGTON, Mass.--(BUSINESS WIRE)--Infraredx, Inc., a medical device company committed to advancing the diagnosis and management of coronary artery and other vascular diseases, today announced that its TVC Imaging System™ for the true vessel characterization of coronary artery disease will be featured in panels, live case presentations and a plenary session at EuroPCR 2012, being held May 15-18, 2012 at the Palais des Congrès in Paris. The...  

A day after a study in the journal Lancet challenged the long-standing notion that raising levels of HDL -- commonly known as "good" cholesterol -- prevents heart attacks, top cardiology experts differed on whether the research really means the end of the road for therapies aimed at boosting HDL levels to beat back heart disease.  

HDL cholesterol, known as "good cholesterol" has for years been an enigma. It's not always good, depending on the type. It is the pathology state which, in part, determines how HDL acts - whether HDL is good or bad. If someone has diabetes, heart disease, arthritis, or some other inflammatory condition, their HDL is not as health-promoting as someone who does not have these conditions. High levels of "bad" HDL have been shown to be...  

As a medical student, I'm not really aware of anything that shows that HDL is cardioprotective while taking into account a satisfactory number of confounding factors.However high HDL is *generally* correlated with lower LDL which IS better for your health. Also drugs that increase HDL generally lower your LDL, total cholesterol, total lipids, or all three. ca_aok  

The widely used class of cholesterol-lowering medications known as statins may help elderly patients with high blood pressure avoid developing atrial fibrillation, a heart rhythm abnormality tied to stroke.  

Eating too much red meat, butter and other foods that contain high levels of saturated fats could increase the risk of Alzheimer's, according to a study. US researchers linked to Harvard University found older women who ate lots of food high in saturated fats had worse memories than others. By contrast, those who ate more monounsaturated fats - found in olive oil, sunflower oil, seeds, nuts and avocados...  

Steady increase in the incidence of atherosclerosis is becoming a major concern not only in the United States but also in other countries. One of the major risk factors for the development of atherosclerosis is high concentrations of plasma low-density lipoprotein, which are metabolic products of very low-density lipoprotein (VLDL). VLDLs are synthesized and secreted by the liver. In this review, we discuss various stages through which VLDL...  

BlissTreeGood HDL Cholesterol Won't Protect Against Heart Disease, Says StudyBlissTreeby Briana Rognlin | Leave a comment | Share a Tip A new study was released earlier this week that says HDL–otherwise known as “good cholesterol” by everyone from doctors to the CDC, because of its association with a lower risk of heart disease–may not ...Health roundup: Antibiotic may raise risk of sudden deathMinneapolis Star TribuneStudy: 'Good cholesterol...  

Age may affect coronary flow reserve (CFR) especially in subjects with atherosclerotic risk factors (ARFs). The aim of this prospective, multicenter, observational study was to determine the effects of aging on CFR in patients with normal epicardial coronary arteries and ARFs. Three-hundred-thirty-five subjects (mean age = 61 years) with at least one ARF but normal coronary angiography underwent high-dose dipyridamole stress-echo with Doppler...  

Statin drugs concretize and institutionalize a certain myth about cardiovascular disease that the masses are only now beginning to awaken from, namely, that cardiovascular disease is caused by cholesterol and that cholesterol-suppression "therapy" reduces cardiovascular morbidity and mortality. The 25 billion dollar-a-year commercial apotheosis of Statin drug therapy, purportedly intended to prevent and treat cardiovascular disease...  

Researchers at UC have confirmed that fat surrounding the outside of arteries in humans—particularly the left coronary artery—may influence the onset of coronary artery disease, or atherosclerosis, which is the leading cause of death in the U.S.  

Researchers have confirmed that fat surrounding the outside of arteries in humans -- particularly the left coronary artery -- may influence the onset of coronary artery disease, or atherosclerosis, which is the leading cause of death in the US.  

(NaturalNews) Systemic inflammation is a primary factor in the development and progression of many chronic conditions ranging from heart disease and stroke to diabetes, dementia, and cancer. Most people have no idea that their risk of these conditions is ...  

The data, from a large-scale genetic analysis, throw cold water on the potential clinical benefits of raising HDL-cholesterol levels to reduce the risk of MI, say investigators. Heartwire  

Background A growing body of literature links nutrition to mood, especially in epidemiological surveys, but there is little information characterizing food intake in people with diagnosed mood disorders. Conclusions Much research has proposed ...  

Raising levels of “good’’ cholesterol may not be so good for you after all. A study published Wednesday by Boston-area scientists challenges the long-held idea that HDL cholesterol actively protects against heart disease, finding that people with genes that boosted their HDL did not have a lowered risk of heart attacks. The study appearing in the medical journal The Lancet examined the health of more than 100,000 people, some of them with...  

This mesh comes with the coronary arteries being expanded. An important benefit about this new stent is it's coated with Zotarolimus, a medication that allows you prevent the artery from shrinking again once the new tissue begins to create. Preventing the ...  

Buy Lipitor, Generic Atorvastatin and Canada prescription drugs from our generic pharmacy Blue Sky.By taking it or its generic counter-part you will lower your cholesterol which will in turn help to prevent heart disease and hardening of the arteries PRLog ...  

The Food and Drug Administration recently informed the public that some patients reported memory loss while taking statins, a popular class of cholesterol reducing medications. This article clarifies this issue for patients.Contributor: Dr. Omudhome OgbruPublished: May 14, 2012  

... see if adding extended-release niacin to raise HDL cholesterol in patients who had already achieved a very low LDL cholesterol level (40 to 80 mg/dL) with simvastatin (and ezetimibe if needed) would lead to further risk reductions, compared with the placebo group.  

Buried in the ‘Research’ section of the New York Times: Doubt Cast on the ‘Good’ in ‘Good Cholesterol’ May 16, 2012 The name alone sounds so encouraging: HDL, the “good cholesterol.” The more of it in your blood, the lower your risk of heart disease. So bringing up HDL levels has got to be good [...]  

Background: Postoperative atrial fibrillation (POAF) is the most common complication after coronary artery bypass grafting (CABG). The preventive effect of magnesium on POAF is not well known. This meta-analysis was undertaken to assess the efficacy of intravenous magnesium on the prevention of POAF after CABG. Methods: Eligible studies were identified from electronic databases (Medline, Embase, and the Cochrane Library). The primary outcome...  

Background: Statins have several effects beyond their well-known antihyperlipidemic activity, whichinclude immunomodulatory, antioxidative and anticoagulant effects. In this study, we havetested the possible antimicrobial activity of statins against a range of standard bacterial strainsand bacterial clinical isolates. Methods: Minimum inhibitory concentrations (MIC) values were evaluated and compared among threemembers of the statins drug...  

Cholesterol-lowering drugs can benefit even apparently healthy people with no previous history of heart disease, a study has found. Many doctors already take the pills which lower levels of cholesterol in the blood The findings suggest everyone over a ...  

TUESDAY, May 22 (HealthDay News) -- For older women, higher saturated fatty acid (SFA) intake correlates with worse global cognition and verbal memory trajectories, while higher intake of monounsaturated fatty acids (MUFA) correlates with ...  

Green acres is the place for me. Farm livin' is the life for me. City centre residents who took part in a study were almost twice as likely to suffer from coronary artery calcification (CAC), which can lead to heart disease, than people who lived in less polluted urban and rural areas, according to research published in the May issue of the Journal of Internal Medicine. Researchers spoke to 1,225 men and women aged 50 and 60 years of age...  

Omega-3 (-3) very long chain polyunsaturated fatty acids (VLC-PUFAs) such as eicosapentaenoic acid (EPA; 20:5 5,8,11,14,17) and docosahexaenoic acid (DHA; 22:6 4,7,10,13,16,19) have been shown to have significant roles in human health. Currently the primary dietary source of these fatty acids are marine fish; however, the increasing demand for fish and fish oil (in particular the expansion of the aquaculture industry) is placing enormous...  

City centre residents who took part in a study were almost twice as likely to suffer from coronary artery calcification (CAC), which can lead to heart disease, than people who lived in less polluted urban and rural areas, according to research published in the May issue of the Journal of Internal Medicine.  

As dietitians committed to recipe makeovers, we tend to shy away from foods rich in saturated fat. So we’ve never cooked much with coconut milk (though we do like the light variety) or coconut oil. Coconut oil is high in saturated fat, but it turns out that the kind of saturated fat in coconut oil — lauric acid — can actually help to raise HDL cholesterol, the so-called good kind. Our trusted interns, Yvonne and Tashia, are currently doing...  

It’s also been clearly shown that statins, drugs that lower LDL cholesterol, decrease cardiovascular risk. But it has been unclear whether the association with HDL was analogous -- whether raising HDL levels would be protective. To test this ...  

Pfizer Q1 profit falls 19 pct on generic Lipitor Associated Press Copyright 2012 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. Updated 05:45 a.m., Tuesday, May 1, 2012 Pfizer Inc. said Tuesday that its first-quarter profit fell 19 percent, mainly because new generic competition to its blockbuster cholesterol pill Lipitor cut U ...  

does any one have a statin drug horror story.big pharma is out to damage you,all for the love of money and dr.'s are out to get kick backs.folk's do your research.in six yr.s my husband has memory loss even after a year of being off, his muscles are ... From the experience, I Have Tons of Medical Problems  

Current low-density lipoprotein, “LDL” cholesterol, lowering therapies are effective to reduce the risk of coronary events ... shown to be inversely related to cardiovascular disease risk. HDL promotes the flux of excess cholesterol from ...  

Cox proportional hazards analysis including established cardiovascular risk factors revealed an independent ... and in particular EDNRA in coronary disease. Coronary heart disease (CHD) encompasses a range of conditions including unstable ...  

Pfizer, the world's biggest drug maker, said Tuesday that its first-quarter profit fell 19 percent from a year earlier due to generic competition for its blockbuster anti-cholesterol pill Lipitor.Pfizer said net income was $1.8 billion in the first three months of the year, or 24 cents per share, compared with $2.2 billion in the year ago period.Excluding special items, Pfizer earned 58 cents per share, better than the 56 cents forecasted by...  

Keeping Low-Density Lipoprotein or LDL (known as bad cholesterol) under check is good for your heart. But raising levels of good cholesterol may not have any impact on your heart disease risk, a new study says.  

Cancer is the leading cause of death late after heart transplantation. Now, new research shows that statins, immunomondulatory drugs, may benefit patients beyond their lipid lowering effects. Researchers in Zurich are currently investigating the impact of ...  

Omega-3 fatty acid supplements have well-established healthy effects on the heart. But a study suggests these heart-healthy effects don’t include improving diastolic function, the ability of the heart to relax and efficiently fill with blood.  

There are over 32 million Americans, aged 45 and older that are currently taking cholesterol lowering drugs according to reported Government health survey statistics. Half of these are men ages 65-74 and 39% are women ages 75 plus. Cholesterol ...  

(Ivanhoe Newswire) - Cancer is the leading cause of death late after heart transplantation. Now, new research shows that statins, immunomondulatory drugs, may benefit patients beyond their lipid lowering effects. Researchers in Zurich are currently ...  

Keeping Low-Density Lipoprotein or LDL (known as bad cholesterol) under check is good for your heart. But raising levels of good cholesterol or HDL - as often suggested by medical experts - may not have any impact on your heart disease risk, a new study says.  

RedOrbitConflicting Opinions On HDL As 'Good' CholesterolRedOrbitHigh-density lipoprotein, otherwise known as HDL, was thought to be “good” cholesterol. However, a new study, based on databases of genetic information, disproves the HDL theory and states that rising HDL may not have any change to heart disease risk.and more »  

A heart-healthy diet plays an important role in keeping your cholesterol levels within a healthy range. But if you're not accustomed to watching what you eat, beginning a heart-healthy diet may seem like a horrendous task....Read Full Post  

NewsolioTips to raise HDL 'good' CholesterolCanIndia NewsYou probably know all about the two types of cholesterol: HDL and LDL. Too much “bad” (LDL) cholesterol can gunk up your blood and clog your arteries. But “good” (HDL) cholesterol acts like a housekeeper for your blood, mopping up excess LDL and ...AIM-HIGH fell short, leaving experts looking for reasons in new reviewTheHeart.OrgExercise benefits in Heart DiseasesNewsolio (blog)Fiber...  

Omega-3s are composed of DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid). According to Dr. William Harris, a research professor at the Sanford School of Medicine in South Dakota, and an established authority on omega-3 fats ...  

Millions of people who have received unhealthy cholesterol test results are prescribed statin medications. New research indicates that these drugs may improve the recovery of patients who have suffered strokes. The findings could lead to major ...  

Giving stroke victims cholesterol-lowering statins while they are still in the hospital increases the likelihood that they will survive the stroke and be able to go home, researchers reported Tuesday. It has been known that giving the drugs to a ...  

While annual sales of statin drugs have reached 29-billion dollars a year, globally, new concerns are being raised by a broad range of health and consumer advocacy organizations around the world regarding the growing body of clinical research indicating they may be causing far greater harm than good. Despite the success of statin drugs for lowering cholesterol, over 300 health problems have been linked to this chemical class of drugs in peer...  

In addition to upregulating the hepatic LDL receptors, resulting in lower serum LDL levels, statins have important pleiotropic effects including improved endothelial function, stabilization of atherosclerotic plaque and decreased vascular inflammation.  

Xarelto is already approved for use to reduce the risk of blood clots in the legs and lungs of people who have had knee or hip replacement surgery. It is also approved to prevent strokes among people with a type of irregular heartbeat called atrial fibrillation.  

All over 50s should be taking statins to avoid heart attack (Thinkstock photos/Getty Images) Everyone over the age of 50 should be given statins because the cholesterol-lowering drugs can reduce the chances of a heart attack or stroke even in ...  

1. Introduction The statin industry has enjoyed a thirty year run of steadily increasing profits, as they find ever more ways to justify expanding the definition of the segment of the population that qualify for statin therapy. Large, placebo-controlled studies have provided evidence that statins can substantially reduce the incidence of heart attack. High serum cholesterol is indeed correlated with heart disease, and statins, by interfering...  

Statins prevent cancer and reduce death from all causes in heart transplant recipients ... During follow up, cancer was diagnosed in 108 patients (42%). Statins reduced the risk of any cancer by 65% (p=0.0001). Eight years after transplantation ...  

The risk of incident cancer of any type was roughly halved among statin users in a single center's heart transplantation registry. The cumulative rate at 8 years reached 13% with statin use but 34% without it (P<0.003), Georg M. Froelich ...  

New lipid-lowering agent offers a fresh approach to treatment of elevated cholesterol. The biological therapy reduces cholesterol in difficult to treat individuals.Contributor: Dr. Sharon A. TakiguchiPublished: May 03, 2012  

Statins, cholesterol-lowering drugs, could benefit people who are completely healthy, according to a new study published on Thursday. The study, published in The Lancet, suggests that everyone over 50 could benefit from taking the drugs ...  

saturday May 19, 2012 (foodconsumer.org) -- An article released in the Journal of Internal Medicine says different types of dietary fats have different effects on the risk of coronary heart disease, which is the major heart disease and a leading killer in ...  

WILMINGTON, Del., May 01, 2012 (BUSINESS WIRE) -- AstraZeneca (NYSE:AZN) today announced results of the LUNAR (Limiting UNdertreatment of Lipids in Acute Coronary Syndrome with Rosuvastatin) study, which showed that CRESTOR 40mg significantly ...  

People who ate a combination of recognised cholesterol-lowering foods for 6 months more effectively lowered their LDL (or bad) cholesterol than those who consumed a therapeutic low-saturated fat diet. These are the findings published in the Journal of the ...  

Natural remedies and cures help maintain normal levels of cholesterol without the need to take pharmaceutical drugs that produce dangerous side effects. Red Yeast Rice Chinese red yeast rice helps balance normal levels of cholesterol. Red yeast rice ...  

The good fats are polyunsaturated and monounsaturated fats. Good fats can help lower LDL (bad) cholesterol and prevent heart disease. There are two types of polyunsaturated fats: omega-3 fatty acids and omega-6 fatty acids. Omega-3's come mainly ...  

AstraZeneca (NYSE: AZN) today announced results of the LUNAR (Limiting UNdertreatment of Lipids in Acute Coronary Syndrome with Rosuvastatin) study, which showed that CRESTOR 40mg significantly decreased LDL-C or “bad” cholesterol and increased HDL-C ...  

New study finds cholesterol-lowering drugs can also help healthy people Credit: ITV News In an accompanying article, Professor Shah Ebrahim and Dr Juan Casas from the London School of Hygiene and Tropical Medicine wrote: "Because most people ...  

NEW YORK, May 23, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Generics in Cardiovascular Diseases Market to 2018 - Loss of Lipitor Market Exclusivities and Impending Patent ...  

In fact, some good cholesterol may harm your heart. When is good cholesterol bad? Researchers at Harvard School of Public Health (HSPH) discovered that a small protein called apolipoprotein C-III (apoC-III) may increase the risk of heart disease when it is ...  

The study, from researchers at Oxford University, found that statins safely reduce the ... The researchers found that statins reduced the risk of serious vascular events by 21 per cent in each of the 5 risk groups for each unit reduction (1 mmol/L) in ...  

Family Practice News Digital NetworkLowering Cholesterol in Childhood Pays Off LaterFamily Practice News Digital NetworkCHICAGO – Lowering LDL cholesterol early in life would prevent three times more cardiovascular events per unit of LDL-reduction compared to the current practice of initiating LDL-lowering statin therapy decades later, based on the findings of a novel ...  

For the first time, researchers at the University of California, San Diego have peered inside a living mouse cell and mapped the processes that power the celebrated health benefits of omega-3 fatty acids. More profoundly, they say their findings ...  

It is important to keep healthy lifestyle to sustain your health. One way to improve your health is by reducing your cholesterol level. Our blood stream contains cholesterol and other components needed by our body. It will help in creating ...  

With regard to addressing non-LDL cholesterol in patients with PAD, the atherogenic lipid profile with low HDL-C, elevated triglycerides and increased levels of small dense LDL has been studied in patients with symptomatic lower extremity PAD. The presence ...  

In the wake of U.S. health regulators’ orders to put warning labels on cholesterol-lowering drugs known as statins because they can cause muscle weakness, diabetes, memory loss and depression, a group of researchers are suggesting that everybody over age 50 should be on statins regardless of the side effects. The reason, the researchers said, is that it’s more important to avoid heart attacks and strokes than to worry about possible side...  

"HDL levels are related to risk, but that doesn't mean that raising HDL is beneficial," he said. "What we do know is that lowering LDL has a big impact on risk, so the take-home message remains, 'Get those LDL numbers down,'"  

Washington, April 21 (ANI): Fat surrounding the outside of arteries in humans-particularly the left coronary artery-may influence the onset of coronary artery disease, or atherosclerosis, researchers at UC have revealed. These findings may help in ...  

PITTSBURGH and LYON, France, May 11, 2012 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today announced that it has launched Atorvastatin Calcium Tablets, 10 mg, 20 mg, 40 mg and 80 mg in France, Belgium, the UK,  

[11] In a prospective, observational cohort study, 1374 patients with PAD were followed for an average of 6.4 ± 3.6 years to determine whether higher doses of statins and lower levels of LDL-C were associated with improved cardiovascular outcomes.  

My wife took Lipitor to lower her cholesterol ... and Lisa Gill of Consumer Reports on the pros and cons of statins. We discuss ways other than statins to reduce the risk of heart disease in our Guide to Cholesterol Control and Heart Health.  

(HealthDay News) – Elderly patients with hypertension who receive statin therapy have a reduced risk of atrial fibrillation (AF), with statins particularly effective for those with a CHADS 2 (congestive heart failure, hypertension, age ≥75 years ...  

First, the good. Unsaturated fats, which include both monounsaturated fats and polyunsaturated fats, are found primarily in plant-based sources and can decrease cholesterol levels and inflammation and regulate heart rhythms, according to Harvard ...  

It is a well known fact that consuming foods containing saturated fats or trans fats is bad for your heart. Now researchers have linked "bad" fat - saturated fat - with worse overall cognitive function and memory in women over time. By contrast ...  

NEW YORK (MarketWatch) -- Mylan Inc. said Friday it's launching sales of its generic version of the popular cardiovascular medicine Lipitor in France, Belgium, the U.K., the Netherlands and Ireland after winning regulatory approvals in each country. Atorvastatin Calcium serves as a generic version of Pfizer's Lipitor drug for the prevention of heart attacks. Market Pulse Stories are Rapid-fire, short news bursts on stocks and markets as they...  

ScienceDaily (Apr. 20, 2012) — Researchers at UC have confirmed that fat surrounding the outside of arteries in humans -- particularly the left coronary artery -- may influence the onset of coronary artery disease, or atherosclerosis, which is the ...  

Naturally, this correlation made HDL levels seem an attractive target for drugs to reduce the risk of heart disease. To help doctors understand whether this was the case, Kathiresan and his colleagues looked at a group of people who had higher HDL levels ...  

This work showed beyond any reasonable doubt that many different methods of reducing a person's LDL levels lower the risk of heart disease. Large-scale studies of genetic variation tied to LDL have been revealing, but the data on HDL are not so clear.  

Given the symptoms of leg discomfort and reduction in exercise capacity ... Key clinical trial in the management of dyslipidemia in patients with peripheral arterial disease (PAD). Aung PP, Maxwell H, Jepson RG, Price J, Leng GC. Lipid-lowering for ...  

taking statins can reduce their risk by a fifth. "International criteria says cholesterol-lowering statins should be prescribed to people who have diagnosed heart disease or those with at least a 20% risk of suffering a nonfatal heart attack or stroke ...  

The latest HDL (good cholesterol) study reports that having a high HDL level may not cut your heart disease risk, according to a May 16, 2012 NY Times article,  HDL ‘Good Cholesterol’ Found Not to Cut Heart Risk. Perhaps protection against ...