Donating Plasma

Blood plasma is the liquid component of blood. Plasma is the largest single component of blood, making up about 55% of total blood volume. Blood plasma contains many vital proteins including fibrinogen, globulins and human serum albumin.

Serum refers to blood plasma in which clotting factors (such as fibrin) have been removed naturally by allowing the blood to clot prior to isolating the liquid component.

Plasma is mainly composed of water, blood proteins, and inorganic electrolytes. It serves as transport medium for glucose, lipids, amino acids, hormones, metabolic end products, carbon dioxide and oxygen.

Learn more about blood donations, blood plasma donations, and related health topics.

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Protein glycation inhibitory activity of wheat bran feruloyl oligosaccharides

Written by BurtonLee on

From: albumin-research.blogspot.com

Protein glycation is believed to play an important role in the development of long-term disorders associated with diabetes. Water-soluble feruloyl oligosaccharides (FOs) from wheat bran, the ferulic acid esters of oligosaccharides, have been reported as natural antioxidants. The present work assesses the chelating activity of FOs and their inhibition of protein glycation in a bovine serum albumin (BSA)/glucose system, using fluorescence spectroscopy and sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE). FOs exhibited an effective ferrous ion chelating activity, and quenched the fluorescence intensity of glycated bovine serum albumin (BSA) in a dose-dependent manner with 64.0% of inhibition at 1.0 mg/ml. Further, the formation of advanced glycation end products in the tested system was significantly decreased by FOs, as shown by SDS–PAGE. These data indicate that FOs might be beneficial as glycation inhibitors under specified conditions.

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