Epigenetics
Epigenetics means "above genetics". It deals with how the genes are switched on and off.
In trying to explain psychiatric disorders, genes simply cannot tell the whole story. The real answers are in the interaction of genes and the environment. Post-traumatic stress disorder requires some trauma, for instance, and people, for the most part, arent born depressed. Now research has revealed one mechanism by which a stressful experience changes the way that genes are expressed in the rat brain. The discovery of epigenetic...
From pr-usa.net
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- The molecular basis for stability of heterochromatin-mediated silencing in... (biomedcentral.com)
- CpG_MI: a novel approach for identifying functional CpG islands in mammalian... (nar.oxfordjournals.org)
What has Science discovered so far about the question over Homosexuality and its inheritable biologic or lifestyle choice debate? Is being Gay a choice? Or are people born Gay? Nature or Nurture?
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From del.icio.us
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HOUSTON -- (November 6, 2009) -- The five recipients of the 2009 Michael E. DeBakey, M.D., Excellence in Research Awards at Baylor College of Medicine explore a variety of phenomena in their labs gene therapy for diabetes, epigenetic inheritance, the mechanisms of DNA recombination and the regulation of ovarian follicular development, ovulation and subsequent events.
From media-newswire.com
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- Epigenetics (technorati.com)
- Epigenetics - Wikipedia, the free encyclopedia (del.icio.us)
This article describes the delicate balance between nature and nurture as one grows and develops in the dynamic environment. Topics explored include: heritability of traits, DNA methylation, genotype variations, and individual epigenetic predisposition.Contributor: Brooke AutowskiPublished: Nov 16, 2009
From associatedcontent.com
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- Epigenetics: Nurture Takes the Spotlight (associatedcontent.com)
- How epigenetics is changing our fight with disease (abc.net.au)
The Hopkins Epigenetic Center received $16.8 million of this grant to be given over a span of five years.
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From jhunewsletter.com
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SuperGen, Inc. (NASDAQ:SUPG) and GlaxoSmithKline (NYSE:GSK) have entered into a multi-year collaboration to discover and develop cancer therapeutics based on epigenetic targets. Epigenetics refers to the regulation of genes with mechanisms other than changes to the underlying DNA sequence. Epigenetic processes are widely believed to play a central role in the development and progression of almost all cancers.
Under the terms of the deal...
From pr-inside.com
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- Researchers to focus on abnormal fetal growth and chronic kidney disease (news-medical.net)
Background:
We have previously shown that deviations from the average transcription profile of a group of functionally related genes are not only heritable, but also demonstrate specific patterns associated with age, gender and differentiation, thereby implicating genome-wide nuclear programming as the cause. To determine whether these results could be reproduced, a different micro-array database (obtained from two types of muscle tissue...
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From biomedcentral.com
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Background:
Epigenetic modification of DNA via methylation is one of the key inventions in eukaryotic evolution. It provides a source for the switching of gene activities, the maintenance of stable phenotypes and the integration of environmental and genomic signals. Although this process is widespread among eukaryotes, both the patterns of methylation and their relevant biological roles not only vary noticeably in different lineages, but often...
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From biomedcentral.com
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Motivation: The highly coordinated expression of thousands of genes in an organism is regulated by the concerted action of transcription factors, chromatin proteins and epigenetic mechanisms. High-throughput experimental data for genome wide in vivo protein–DNA interactions and epigenetic marks are becoming available from large projects, such as the model organism ENCyclopedia Of DNA Elements (modENCODE) and from individual labs. Dissemination...
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From bioinformatics.oxfordjournals.org
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The National Institutes of Health announced today that it will fund 22 grants on genome-wide studies of how epigenetic changes -- chemical modifications to genes that result from diet, aging, stress, or environmental exposures -- define and contribute to specific human diseases and biological processes.
From news-medical.net
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- NIH awards $62M for genome-wide epigenetic research (p.moreover.com)
