Getting pregnant over 40
Birth in your 40's now is considered to be late, yet it was quite common in previous centuries. Women have been having babies well into their 40's, and even their 50's - since the beginning of time. "In 2005, there were more than 104... [more]
Birth in your 40's now is considered to be late, yet it was quite common in previous centuries. Women have been having babies well into their 40's, and even their 50's - since the beginning of time.
"In 2005, there were more than 104,000 births in the United States to women ages 40 through 44, and over 6,500 to women 45 and older. In 2004, there were 1,786 live births to women over 42, using donor eggs."
Sharing articles I find, discussing options you might consider & suggesting what might help. Lots of inspiring stories of pregnancy & birth, both spontaneous and assisted.
Researchers discover a gene that regulates, blocks ovulation
Montreal, July 17, 2008 – A group of Canadian and European researchers have unlocked the mystery of a gene with the potential to both regulate and block ovulation. The new study – a collaboration between the Université de Montréal in Canada and the Institut de génetique et biologie moléculaire et cellulaire of the Université de Louis Pasteur, Strasbourg, France – is published in the latest issue of the journal Genes & Development."Our findings demonstrate that the Lrh1 gene is essential in regulating ovulation," said Bruce D. Murphy, director the Animal Research Centre at the Faculty of Veterinary Medicine and an adjunct professor of and obstetrics and gynaecology at the Faculty of Medicine of the Université de Montréal. "Until this point, the role of Lrh1 in female fertility was unclear, but we have found the gene regulates multiple mechanisms of ovulation and may affect fertilization."
To reach their conclusions, the research team developed a new type of genetically modified mouse whose Lrh1 gene was selectively blocked in the ovary. They found that deletion of the Lrh1 gene effectively stopped ovulation. "This discovery means we can envision new contraceptives that selectively stop ovulation," said Dr. Murphy. "If created, these new contraceptives would be more effective and produce less side-effects than current steroid-based forms of birth control."
What's more, the findings could lead to the development of pharmaceuticals that activate the Lrh1 gene, which may prove critical in giving infertile couples hope in producing children. "This is an important development, since 15 percent of couples are infertile," said Dr. Murphy. "The widespread role of this gene in the ovary indicates that it may be targeted to stimulate ovulation and, eventually, conception."
Source: http://www.eurekalert.org/pub_releases/2008-07/uom-rda071708.php
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