Iron Deficiency.

Iron is of great importance in human nutrition. The adult human body contains between 3-4 g of iron, of which 60-70 percent is present in the blood (Hb iron) as circulating iron, and the rest (1 to 1.5 g) as storage iron. Each gram of hemoglobin contains about 3.34 mg of iron. There are two types of iron, haem-iron and non-haem iron. Haem iron is better absorbed than non-haem iron. Foods rich in haem-iron are liver, meat, poultry and fish. They are not only source of willingly obtainable iron but they also encourage the absorption of non-haem iron in plant foods eat at the ... Read Full Story

Readers of these pages probably recall that obesity is commonly associated with increased markers of inflammation . It is now, therefore, often referred to as a state of chronic low-grade inflammation. Chronic inflammation is commonly associated with anemia even in the presence of adequate iron stores. So is obesity associated with an increased risk for anemia? This question was addressed by Karlee Ausk and George Ioannou from the University of Washington, Seattle, WA in participants of the third National Health and Nutrition Examination Survey (NHANES III) by analysing the relationship between BMI and features of anemia of chronic disease, including low hemoglobin concentration, low ... Read Full Story

By: Vitamin Deficiency Iron Deficiency Anemia iron deficiency anaemia - foto: Medical Education and Research The body needs iron to make hemoglobin. If there isn’t enough iron available , hemoglobin production is limited, which in turns affects the production of red blood cells. Iron deficiency anemia (IDA), often caused by insufficient iron intake, is the major cause of anemia in childhood. Iron deficiency anemia doesn’t develop immediately. Instead, a person progresses through stages of iron deficiency , beginning with iron depletion, in which the amount of iron in the body is reduced while the iron in red blood cells remains constant. If iron depletion ... Read Full Story

Hepatic sinusoidal obstruction syndrome (SOS) is a serious complication in hematopoietic stem cell transplant (HSCT) recipients. To determine the impact of pretransplantation hyperferritinemia on the risk of SOS after HSC transplantation, we retrospectively studied 427 HSCT recipients (179 autologous and 248 allogeneic). Serum ferritin levels were measured before transplantation. Patients with and without a diagnosis of SOS were compared regarding demographics; underlying disease; transplant characteristics; receipt of imatinib, busulfan, total body irradiation, gemtuzumab, vancomycin, acyclovir, or methotrexate; and baseline serum ferritin. Univariate and multivariate (stepwise logistic regression) analyses were performed. SOS was diagnosed in 88 patients (21%) at a median of 10 days (range, ... Read Full Story

Hepatic sinusoidal obstruction syndrome (SOS) is a serious complication in hematopoietic stem cell transplant (HSCT) recipients. To determine the impact of pretransplantation hyperferritinemia on the risk of SOS after HSC transplantation, we retrospectively studied 427 HSCT recipients (179 autologous and 248 allogeneic). Serum ferritin levels were measured before transplantation. Patients with and without a diagnosis of SOS were compared regarding demographics; underlying disease; transplant characteristics; receipt of imatinib, busulfan, total body irradiation, gemtuzumab, vancomycin, acyclovir, or methotrexate; and baseline serum ferritin. Univariate and multivariate (stepwise logistic regression) analyses were performed. SOS was diagnosed in 88 patients (21%) at a median of 10 days (range, ... Read Full Story