Iron is of great importance in human nutrition. The adult human body contains between 3-4 g of iron, of which 60-70 percent is present in the blood (Hb iron) as circulating iron, and the rest (1 to 1.5 g) as storage iron. Each gram of hemoglobin contains about 3.34 mg of iron. There are two types of iron, haem-iron and non-haem iron. Haem iron is better absorbed than non-haem iron. Foods rich in haem-iron are liver, meat, poultry and fish. They are not only source of willingly obtainable... Read Full Story
Readers of these pages probably recall that obesity is commonly associated with increased markers of inflammation . It is now, therefore, often referred to as a state of chronic low-grade inflammation. Chronic inflammation is commonly associated with anemia even in the presence of adequate iron stores. So is obesity associated with an increased risk for anemia?
This question was addressed by Karlee Ausk and George Ioannou from the University of Washington, Seattle, WA in participants of... Read Full Story
By: Vitamin Deficiency
Iron Deficiency Anemia
iron deficiency anaemia - foto: Medical Education and Research
The body needs iron to make hemoglobin. If there isn’t enough iron available , hemoglobin production is limited, which in turns affects the production of red blood cells. Iron deficiency anemia (IDA), often caused by insufficient iron intake, is the major cause of anemia in childhood.
Iron deficiency anemia doesn’t develop immediately. Instead, a person progresses through... Read Full Story
Hepatic sinusoidal obstruction syndrome (SOS) is a serious complication in hematopoietic stem cell transplant (HSCT) recipients. To determine the impact of pretransplantation hyperferritinemia on the risk of SOS after HSC transplantation, we retrospectively studied 427 HSCT recipients (179 autologous and 248 allogeneic). Serum ferritin levels were measured before transplantation. Patients with and without a diagnosis of SOS were compared regarding demographics; underlying disease; transplant... Read Full Story
Hepatic sinusoidal obstruction syndrome (SOS) is a serious complication in hematopoietic stem cell transplant (HSCT) recipients. To determine the impact of pretransplantation hyperferritinemia on the risk of SOS after HSC transplantation, we retrospectively studied 427 HSCT recipients (179 autologous and 248 allogeneic). Serum ferritin levels were measured before transplantation. Patients with and without a diagnosis of SOS were compared regarding demographics; underlying disease; transplant... Read Full Story
I haven’t slept well for the last few nights….and counting sheep hasn’t helped! I’m anemic again. Low iron levels mean low levels of oxygen in my blood…..leading to shortness of breath, insomnia, dizziness, and headaches.
Ordinarily, the recommended daily iron intake for a woman my age is 18 mg. I take 225 mg…….on an empty stomach, with vitamin C…..to aid absorption……and still, I’m anemic.
On a funny note……on my blog stats page this morning, I learned that one of the search engine... Read Full Story
What Is ? Anemia is a condition that develops when your blood lacks enough healthy red blood cells. These cells are the main transporters of oxygen to organs. If red blood cells are also deficient in hemoglobin, then your body isn't getting enough iron. Symptoms of anemia -- like fatigue -- occur because organs aren't getting enough oxygen. Anemia is the most common blood condition in the U.S. It affects about 3.5 million Americans. Women and people with chronic diseases are at increased... Read Full Story
Increases in risk of breast cancer in successive generations of migrants to the United States from China and rapid temporal changes in incidence rates in China following social and economic changes clearly implicate environmental factors in the etiology of this disease. Case-control and cohort studies have provided evidence that at least some of these factors may be dietary. Iron, an essential element necessary for cell function, has also been demonstrated to have potential carcinogenic and... Read Full Story
Ferritins are characterized by highly conserved three-dimensional structures similar to spherical shells, designed to accommodate large amounts of iron in a safe, soluble and bioavailable form. They can have different architectures with 12 or 24 equivalent or non-equivalent subunits, all surrounding a large cavity. All ferritins readily interact with Fe(II) to induce its oxidation and deposition in the cavity in a mineral form, in a reaction that is catalyzed by a ferroxidase center. This is... Read Full Story
Cardiovascular impairment is a major cause of morbidity and mortality in patients with thalassemia intermedia. In this study, echocardiographic assessment of left heart condition was performed in patients with thalassemia intermedia, and its relation to hematologic variables—amino terminal pro-brain natriuretic peptide (NT-proBNP) , ferritin , hemoglobin —and liver iron concentration (LIC) was investigated. Echocardiographic assessment was performed using pulse-wave Doppler and tissue Doppler... Read Full Story
