JoJo and her mother reside in New Jersey, and her recording studio is in Manhattan, New York City.
She was home schooled for three years, has stated that "school was definitely a big part of my life". She performs well academically, receiving marks in the As and Bs. JoJo dated American soccer player Freddy Adu from May 2005 until September 2006. Both met on the MTV show Fake ID Club while she was hosting it. JoJo made an appearance in the commentary box at a New England Revolution home game when they were playing D.C. United. Freddy Adu registered an assist in that game.
A Washington Post article in November 2006 reported that the couple split after one year. JoJo mentioned on American Top 40 with Ryan Seacrest that she and Adu were still good friends. JoJo stated that she was single on the October 18, 2006 episode of Live with Regis and Kelly. She was also in the October 2006 issue of Teen People magazine confirming her breakup with Freddy Adu. She said: "I'm single right now and it's good. I'm so young. I'm going to be 16 in December and I'm just so busy. It's hard if you also want to date someone who has a high-profile profession; we were just both consumed with our own world..."
Since 2006 she's a good friend with actress Emma Roberts, Sara Paxton and Robin Williams' daughter Zelda Williams. She appeared with her father on the Behind the scene of JoJo's "Too Little Too Late". On February 28, 2007, she was ranked at number ten in the list of Forbes top twenty earners under 25 with an annual earning of $1 million.
JoJo announced on her MySpace blog that she will be attending Northeastern University,but she will not hold her career and decided to continue to focus on her music career. In July 2009, JoJo was ranked at number five in the list "Barely Legal: The 10 Hottest ’90s Babies" by Complex.com, after Emma Roberts and Willa Holland.