Aims: Serum cystatin C, a novel marker of kidney function, is reported to be superior to serum creatinine as a risk factor for atherosclerotic disease, but associations may vary across vascular beds. Methods and results: A cross-sectional study of chronic kidney disease (CKD) and peripheral arterial disease (PAD) in 3089 adult participants aged 40+ from the 1999–2002 National Health and Nutrition Examination Survey (NHANES). Kidney function, assessed by estimated glomerular filtration rate... Read Full Story
Votrient (pazopanib) is a kinase inhibitor indicated for the treatment of patients with advanced renal cell carcinoma. Votrient is a cancer medication that interferes with the growth of cancer cells and slows their spread in the body. Votrient is used to treat advanced renal cell carcinoma (kidney cancer). Votrient may also be used for other purposes not listed in this medication guide. Read Full Story
How is kidney cancer diagnosed | How is kidney cancer treated | What Is kidney cancer | Kidny Cancer Treatment | Kidney Cancer National Cancer Institute | Kidney Cancer Causes
The kidneys
The kidneys are a pair of organs on either side of the spine in the lower abdomen. Each kidney is about the size of a fist. Attached to the top of each kidney is an adrenal gland. A mass of fatty tissue and an outer layer of fibrous tissue (Gerota’s fascia) enclose the kidneys and adrenal glands... Read Full Story
WASHINGTON (Reuters) - The U.S. Food and Drug Administration's review staff expressed doubts that GlaxoSmithKline Plc's experimental kidney cancer drug Votrient should be approved given concerns about liver injury, documents released on Thursday said. Votrient, also known by its chemical name pazopanib, aims to treat advanced renal cell carcinoma. But while the company's data showed a 5-month improvement in median progression-free survival, the FDA reviewers saw no "statistically significant... Read Full Story
ScienceDaily (Nov. 9, 2009) — cystatin C Research: Declining kidney function is linked to a higher risk of heart failure, heart attack, peripheral arterial disease, and early death in individuals with or without kidney disease, according to a pair of studies appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The findings indicate that poor kidney function may raise an individual's risk for cardiovascular complications. To evaluate heart health, clinicians... Read Full Story
It is not uncommon for people to lose up to 70 percent of their kidney function before developing any symptoms. Many of the causes of kidney failure strike at random, and cannot be predicted or prevented. To look on the bright side, the good thing about having early stage diabetes and hypertension is that they present an opportunity for early diagnosis and prevention of progression of kidney failure to end stage.
The first signs may be general and can include:
changes in frequency and... Read Full Story
Definition
Kidney cancer is a disease in which cancer cells grow in the kidneys. The kidneys are two bean-shaped organs, located just above the waist, on each side of the spine. Their main function is to filter the blood and produce urine by which the body rids itself of waste products and excess water.
Cancer occurs when cells in the body (in this case kidney cells) divide without control or order. Normally, cells divide in a regulated manner. If cells keep dividing uncontrollably... Read Full Story
Sometime ago... ER Doc : Dr Happy, I have a patient for you with a creatinine of 25. Dr. Happy : Hmmmm. Dr. Happy : Dr Renal, I have a patient with a creatinine of 25 Dr Renal : Hmmmm. Dr. Happy : Dr ID, I have a patient of yours with a creatinine of 25 ID Doc : Hmmmm. This was not a known kidney dialysis patient. This was one for my record box. That was a Holy Creatinine Batman Moment. That is impressive. Renal failure is one of those illnesses you can't fake. There is no gray zone. There... Read Full Story
Anything that reduces your immune system strength and functionality can make you more prone to kidney infections. It's a common problem with pregnant women particularly, but diabetics and people with HIV or cancer have lowered immune systems and can often get kidney infections too.
For women, sexual intercourse can sometimes cause a bladder infection which will migrate to the kidneys and cause infections there too. Bladder infections can also be gotten easier by women who do not wipe... Read Full Story
The U.S. Food and Drug Administration today approved Votrient (pazopanib), the sixth drug to be approved for kidney cancer since 2005.
Votrient is an oral medication that interferes with angiogenesis, the growth of new blood vessels needed for solid tumors to grow and survive.
Votrient is intended for people with advanced renal cell carcinoma, a type of kidney cancer in which the cancerous cells are found in the lining of very small tubes (tubules) in the kidney. In 2009... Read Full Story
