Nancy Pelosi was born in Baltimore, Maryland. The youngest of six children, she was involved with politics from an early age. Her father, Thomas D'Alesandro, Jr., was a U.S. Congressman from Maryland and a Mayor of Baltimore. Her brother, Thomas D'Alesandro III, also a Democrat, was mayor of Baltimore from 1967 to 1971, when he declined to run for a second term. Pelosi graduated from Institute of Notre Dame, a Catholic all-girls high school in Baltimore, and from Trinity College (now Trinity Washington University) in Washington, D.C. in 1962. Pelosi interned for Senator Daniel Brewster (D-Maryland) alongside future House Majority Leader Steny Hoyer. She met Paul Frank Pelosi (b. April 15, 1940 in San Francisco, California) while she was attending Trinity College. They married in a Catholic church on September 7, 1963. After the couple married they moved to New York, and then to San Francisco in 1969, where his brother, Ronald Pelosi was a member of the City and County of San Francisco's Board of Supervisors.
After moving to San Francisco, Nancy Pelosi worked her way up in Democratic politics. She was elected as party chairwoman for Northern California on January 30, 1977. She later joined forces with one of the leaders of the California Democratic Party, 5th District Congressman Phillip Burton. And in 1987, after her youngest child became a high school senior, she decided to run for political office.
Pelosi is a board member of the National Organization of Italian American Women.
Nancy Pelosi has five children: Nancy Corinne, Christine, Jacqueline, Paul, and Alexandra, as well as seven grandchildren. Alexandra, a journalist, covered the Republican presidential campaigns in 2000 and made a film about the experience, Journeys with George. In 2007, Christine published a book, Campaign Boot Camp: Basic Training for Future Leaders.