Osamu Shimomura

Alina Simone ‘Beautiful Machine’ Against the backdrop of a tumultuous childhood, her family having fled from Ukraine to the US to avoid the repercussions of her parents having refused KGB recruitment, Alina Simone began her musical career in earnest on the cusp of her teen years. As well as her own tentative material, her early recordings included a clutch of Madonna covers, and she distributed her homemade tapes DIY-style among her friends. Her sharply-titled debut album Placelessness arrived in 2007, quickly followed by last year’s Everyone Is Crying Out To Me, Beware , an homage to the works of Siberian punk poet and songwriter ... Read Full Story

Long-term gene therapy resulted in improved cardiac function and reversed deterioration of the heart in rats with heart failure, according to a recent study conducted by researchers at Thomas Jefferson University ’s Center for Translational Medicine. The study was published online in Circulation .The rats were treated with a gene that generates a peptide called ARKct, which was administered to hearts in combination with recombinant-adeno-associated virus serotype 6 (rAAV6). ARKct works by inhibiting the activation of G protein-coupled receptor kinase 2 (GRK2). GRK2 is a kinase that is increased in heart failure myocardium. Enhanced GRK enzymatic activity contributes to the deterioration of the heart ... Read Full Story

Long-term gene therapy has found to be effective in improving cardiac function and reversing heart damage in heart failure. During the study, the researchers treated the rats with a gene that generates a peptide called ARKct, which was administered to hearts in combination with recombinant-adeno-associated virus serotype 6 (rAAV6) ARKct works by inhibiting the activation of G protein-coupled receptor kinase 2 (GRK2). GRK2 is a kinase that is increased in heart failure myocardium and enhanced GRK enzymatic activity contributes to the deterioration of the heart in heart failure, “The theory is that by inhibiting this kinase, the heart will recover partially due to reversal ... Read Full Story

Wikizines are interactive magazines that anyone can create or edit - and this one is called "Osamu Shimomura". Here you can find fresh voices and respond in real time. Some members write articles about recent news and trends related to the wikizine's topic, others recount relevant personal stories or share their favorite pictures and video clips. Got an interesting idea or story to share with other members of this wikizine? Well, then put on your journalist's cap and add your own article! Read Full Story