A new category of drug brakes the growth of treatment-resistant lung cancer among lab mice, according to a study published on Thursday in the science journal Nature. The new type could add powerfully to a small family of drugs called epidermal growth factor receptor (EPFR) inhibitors, say its finders. It tackles mutations in a specific form of lung tumour that often becomes hardened to frontline treatment, according to the study. The molecule, identified by Pasi Janne and colleagues at the... Read Full Story
NEW YORK (Reuters Health) - Dietary "phytoestrogens" -- plant substances that have weak estrogen-like activity -- have little impact on the risks of developing hormone-sensitive cancers like breast and prostate cancer or colorectal cancers, new research suggests. In a large study of some 25,000 British adults, researchers failed to find any "significant" differences in cancer risk related to dietary intake of these compounds. Phytoestrogens are found in a wide range of foods including dairy... Read Full Story
LONDON (Reuters) - Scientists have identified all the changes in cells of two deadly cancers to produce the first entire cancer gene maps and say the findings mark a "transforming moment" in their understanding of the disease. The studies by international scientists and Britain's Wellcome Trust Sanger Institute are the first comprehensive descriptions of tumor cell mutations and lay bare all the genetic changes behind melanoma skin cancer and lung cancer. "What we are seeing today is going... Read Full Story
Two common forms of cancer have been genetically mapped for the first time, British scientists announced, in a major breakthrough in understanding the diseases. The maps have exposed the DNA mutations that lead to skin and lung cancers, in a discovery scientists said could transform the way these diseases are diagnosed and treated in coming years. All cancers are caused by damage to genes -- mutations in DNA -- that can be triggered by environmental factors such as tobacco smoke, harmful... Read Full Story
NEW YORK (Reuters Health) - An herb used since ancient times to treat liver ailments may help reduce the liver damage caused by some cancer drugs, a study published Monday suggests. In a study of 50 children undergoing chemotherapy for acute lymphoblastic leukemia (ALL), researchers found that an herb called milk thistle appeared to reduce treatment-related liver inflammation. The study, published online in the journal Cancer, is the first clinical trial to test the herb in children... Read Full Story
Mesothelioma is one of the diseases that are related to asbestos exposure, most of the time the type of mesothelioma seen is the Malignant Mesothelioma. However rarely mesothelioma victims can develop a milder tumor called Benign Mesothelioma. Although both are tumor diseases that are caused by exposure to asbestos, there are marked differences between the two types of mesothelioma: - Benign Mesothelioma has a short latency period in contrast to the malignant type which typically has a very... Read Full Story
Gene Mutations Show Roles of Sunlight and Smoking in Cancer | Genetic Map Reveals Mutations From Cancer | Smoking in Cancer
The first genetic maps of lung cancer and melanoma reveal the pivotal role of smoking and sunlight in triggering these two deadly forms of cancer.
In two new studies, researchers have sequenced the genome and mapped the entire series of thousands of genetic mutations that are not inherited but accumulate in the cells to cause small-cell lung cancer and melanoma... Read Full Story
http://www.mesovideolibrary… – Mary Jane was diagnosed with peritoneal mesothelioma, an abdominal cancer caused by asbestos exposures, in 2003. Here she describes the importance of finding a doct…
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Patients with the most common form of lung cancer (non-small-cell lung cancer) who have mutations in the epidermal growth factor receptor (EGFR) gene have significantly improved progression-free survival if they are treated with gefitinib compared with standard chemotherapy. Wherever possible, EGFR genetic testing must be done and gefitinib should be considered as the first-line treatment for …
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Gefitinib improves survival compared with standard chemotherapy in lung... Read Full Story
Mesothelioma cancer which affects the lining of abdominal cavity is called peritoneal mesothelioma. About one-fifth of all the cases of mesothelioma cancer reported are found to be peritoneal mesothelioma. More than women, men become victims of this malady and it is caused due to over exposure to asbestos. The symptoms of the disease start appearing only twenty or thirty years after being exposed to asbestos. Timely diagnosis and treatment is the only way to prolong the lives of the victims... Read Full Story
