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Elsevier's Journal of Clinical Virology in collaboration with the US Centers for Disease Control and Prevention (CDC) announced the publication of a special supplement entitled 'Update on HIV Diagnostic Testing Algorithms'. This timely supplement contains articles which summarize studies since the 2010 US HIV Diagnostics Conference validating the proposed new US HIV diagnostic testing algorithm. In addition, review articles and original...  
From medicalnewstoday.com ()
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A team of scientists from Boston University School of Medicine (BUSM) have identified a novel compound that inhibits viruses from replicating. The findings, which are published online in the Journal of Virology, could lead to the development of highly targeted compounds to block the replication of poxviruses, such as the emerging infectious disease Monkeypox.  
From physorg.com ()
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A team of scientists from Boston University School of Medicine (BUSM) have identified a novel compound that inhibits viruses from replicating. The findings, which are published online in the Journal of Virology, could lead to the development of highly targeted compounds to block the replication of poxviruses, such as the emerging infectious disease Monkeypox. The basic research was led by Ken Dower, PhD, a postdoctoral fellow in the laboratory...  
From medicalnewstoday.com ()
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Elsevier's Journal of Clinical Virology, in collaboration with the Centers for Disease Control and Prevention (CDC), today announced the publication of a special supplement, "Update on HIV Diagnostic Testing Algorithms." This supplement contains  
From feedburner.com ()
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The strangest things have happened in the past 24 hours. 1-- New FDA approved clinical trial of anti-HIV vaccine YAY, right? Except I have no idea what the hell they are proposing to do in this clinical trial, other than what was mentioned in press releases-- Its some kind of killed virus. Why the hell putting one killed virus of a currently innumerable quasispecies will do anything, I have no idea. So I tried to look up some back-info on...  
From scienceblogs.com ()
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Phage + Metal = Battery?

By tims3429 on  From phagehunter.org
By now, many people have read about Angela Belcher , a professor at MIT , and her lab's recent developments in the use of bacteriophages as a componant of batteries. Having had a very distinct privilage to hear her speak yesterday, I wish to share what I have learned. In a broad sense, the goal of her lab is to give inorganic compounds (batteries, medical devices, solar cells, etc), "genetic intelligence." That is, to give the power of evolutionary adaptation and self-correction to inanimate...Read Full Story

Phages With Horns?! What's Next?

By tims3429 on  From phagehunter.org
In the world of phage, uniqueness rules. The total number of phages in the biosphere is dramatic, with estimates numbering the population at 10 31 ! Despite such high numbers, since the discovery of phage no identical phage has been found in the environment twice. They have often been termed "Nature's Most Successful Experiment." Their genomes are in constant flux amoung themselves and their hosts. It therefore should no longer surprise us when we discover a phage that doesn't quite fit the...Read Full Story

Oncolytics: Not just for Myxoma Virus

By tims3429 on  From phagehunter.org
In a previous article, I discussed the use of Myxoma Virus as an oncolytic therapy against malignant gliomas. Recently, I came across a post from The Evilutionary Biologist , pointing to an article describing a modified Herpes Virus as treatment against human sarcomas. This continues to show us that viruses can be highly beneficial to our society. Antibacterial therapy and cancer therapy are just two of the many advances that viruses have been crucial in development. It is my opinion that we...Read Full Story

Bursting the Viral Capsid

By hippocrates on  From virology.wordpress.com
This is a speculative method for bursting open assembled viral capsids, even those inside a human cell, in order to destroy the virion. It has been calculated that, for many viruses, the internal pressure inside the capsid is around 60 atmospheres . The viral DNA is squeezed in so tightly that it actually assumes a crystalline form. References: 1 2 Immediate thoughts that come to my mind are: (a) Can we somehow further raise this internal pressure, so as to burst the capsid? (b) And...Read Full Story

Evolution of Phage Capsid and Genome Size

By tims3429 on  From phagehunter.org
Viruses come in all shapes and sizes. From the very small, such as the picornaviruses or the parvoviruses , to the very large like mimivirus , or the herpesviruses , and poxviruses . These large viruses are not just large in physical size, but in the size of their genomes as well. At the recent 2008 ASM General Meeting , Roger Hendrix of the University of Pittsburgh, laid forth a rather interesting hypothesis as to how large genomes, and the capsids that hold them came into existance and how...Read Full Story
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