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Many Faces - Actors Who've Worn Prosthetic Makeup

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Brad Pitt, 'The Curious Case of Benjamin Button'
Yes, CGI helped Brad Pitt age backwards in The Curious Case of Benjamin Button. But there were plenty of scenes where the actor relied on prosthetic makeup to change his appearance. The film's producer, Frank Marshall, told Variety in 2008 that Pitt often had to spend up to five hours at time in the makeup chair for his role.