Rick Moranis
The SCTV, Ghostbusters and Honey, I Shrunk the Kids star was beloved by peers and fans alike, but he took a break from acting after the death of his wife, Ann Belsky, in 1991. He told USA Today, "I'm a single parent and I just found that it was too difficult to manage raising my kids and doing the traveling involved in making movies. So I took a little bit of a break. And the little bit of a break turned into a longer break, and then I found that I really didn't miss it." Moranis was asked to do a cameo in 2016's Ghostbusters. He declined but told THR he still wasn't retired in a 2015 interview.