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John and Jenny and Marley
Marley and Me (2008)

Yes, Marley and Me is totally manipulative emotionally, but it's pretty hard not to love this dog story. John and Jenny Grogan (Owen Wilson, Jennifer Aniston) adopt a rambunctious yellow Lab, Marley, who upends their life by getting into tons of trouble. John can't get enough, but Jenny struggles when their kids are born. In the end, they become a tight family and it's mostly thanks to the crazy dog.