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Extensively drug-resistant tuberculosis (XDR-TB) is defined as tuberculosis that is resistant to rifampicin and isoniazid (resistance to these first line anti-TB drugs defines Multi-drug-resistant tuberculosis), as well as to any member of the quinolone family and at least one of the following second-line TB treatments: kanamycin, capreomycin, or amikacin.
The old case definition of XDR-TB is MDR-TB that is also resistant to three or more of the six classes of second-line drugs. This definition should no longer be used.
The principles of treatment for MDR-TB and for XDR-TB are the same. The main difference is that XDR-TB is associated with a much higher mortality rate than MDR-TB, because of a reduced number of effective treatment options.
The epidemiology of XDR-TB is currently not well studied, but it is believed that XDR-TB does not transmit easily in healthy populations, yet is capable of causing epidemics in populations which are already stricken by HIV and therefore more susceptible to TB infection.
Source:
http://en.wikipedia.org/wiki/XDR-TB
The old case definition of XDR-TB is MDR-TB that is also resistant to three or more of the six classes of second-line drugs. This definition should no longer be used.
The principles of treatment for MDR-TB and for XDR-TB are the same. The main difference is that XDR-TB is associated with a much higher mortality rate than MDR-TB, because of a reduced number of effective treatment options.
The epidemiology of XDR-TB is currently not well studied, but it is believed that XDR-TB does not transmit easily in healthy populations, yet is capable of causing epidemics in populations which are already stricken by HIV and therefore more susceptible to TB infection.
Source:
http://en.wikipedia.org/wiki/XDR-TB
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(AP) -- The World Health Organization urged Asian countries on Monday to take action against the growing threat of drug-resistant tuberculosis, warning that...
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Enews 2.0Officials Praise New Test for Drug-Resistant TBNew York Times - 8 hours agoBy LAWRENCE K. ALTMAN A new test that can detect multiple-drug-resistant tuberculosis in two days instead of the standard two to three months promises to help significantly improve treatment and...
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Doctors in Glasgow are treating Scotland's first diagnosed case of the drug-resistant XDR tuberculosis strain. The man who has the XDR-TB strain is reported to have come to the UK from Somalia. He is now in isolation at the Gartnavel General Hospital. The "super strength" strain of the disease is extremely resistant to traditional antibiotics and has to be treated with a cocktail of drugs. Doctors have said there is no risk to the general public. Did you hear that, Doctors say there is...
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iPodGod
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An estimated 70,000 people detected with multi-drug resistant tuberculosis (MDR-TB) require quality second-line treatment in India, World Health Organisation (WHO) experts say.
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Human immunodeficiency virus (HIV) care and treatment programs in resource-limited settings must aggressively address tuberculosis (TB) and the emerging multidrug-resistant TB epidemic to save patient lives and to curb the global TB burden, a major cause of death for persons with HIV.
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Highly
lethal and drug-resistant tuberculosis could pose a threat to global public
health security if Asian nations fail to combat the spread of the disease, the
World Health Organization (WHO) said on Monday.
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From physorg.com
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ATLANTA, July 23 (UPI) -- Tuberculosis occurs most often in the United States in residents born in sub-Saharan Africa and Southeast Asia, researchers say.
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From upi.com
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Context Foreign-born persons accounted for 57% of all tuberculosis (TB) cases in the United States in 2006. Current TB control strategies have not sufficiently addressed the high levels of TB disease and latent TB infection in this population.
Objective To determine the risk of TB disease and...
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From jama.ama-assn.org
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The World Health Organization (WHO) on Monday said Asian nations had failed to rein in the rapid growth of highly lethal, drug-resistant strains of tuberculosis ( TB) and warned that the disease could soon become a serious threat to the region as a ...
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CHICAGO -- Tuberculosis cases continue to fall in the United States, but some immigrants have disturbingly high rates of the disease, according to a study released Tuesday that called for more aggressive action. TB rates were highest among residents ...
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OXFORD, England & ROCKVILLE, Md.-(Business Wire)-July 23, 2008 - The University of Oxford and Emergent BioSolutions Inc. (NYSE:EBS) announced today that they have formed a joint venture, The Oxford-Emergent Tuberculosis Consortium Ltd. (the "Consortium"), to further develop MVA85A, the...
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Tuberculosis (TB) is a major cause of death among those with HIV. Now, researchers are saying improvement in TB prevention is crucial.
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Three men have been arrested in possession of dagga at the Jose Pearson tuberculosis (TB) hospital in Port Elizabeth.
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