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21. Matthew McConaughey, 'Dallas Buyers Club'
Matthew McConaughey spent six months holed up in his Texas home so he could be away from sunlight and any other distractions. For his physical transformation, McConaughey dropped 47 pounds. His goal was to lose seven pounds a week by eating very little fish and vegetables. He became so weak by the time he hit his goal of 135 pounds. “I would do five push-ups and be sore. I would run 30 feet and my legs would lock up," he said.

As a treat, the actor severely limited his options. "I found tapioca pudding and I found the tiniest little antique spoon in New Orleans, a little bitty sugar spoon, and I would eat it with that so it would last longer," McConaughey added.